Melanotan II 10mg

Melanotan II is a synthetic cyclic heptapeptide analogue of alpha-melanocyte stimulating hormone (α-MSH), developed at the University of Arizona in the 1990s. It acts as a non-selective agonist at multiple melanocortin receptors including MC1R, MC3R, MC4R, and MC5R.

The peptide structure (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂) includes a lactam bridge between aspartic acid and lysine residues, creating the cyclic configuration that provides enhanced resistance to enzymatic degradation compared to linear peptides.

Research has examined Melanotan II’s effects on melanogenesis through MC1R activation, as well as its interactions with other melanocortin receptor subtypes involved in energy homeostasis, sexual function, and inflammatory responses. Studies have characterized its binding affinity and selectivity across the melanocortin receptor family.

The non-selective nature of Melanotan II’s receptor activity makes it a useful research tool for studying the broader melanocortin system, while also presenting considerations for interpreting experimental results due to its multiple receptor interactions.

Purity: ≥99% (HPLC)
Form: Lyophilised powder

For research use only. Not for human consumption.